Simultaneous QTL detection and genomic breeding value estimation using high density SNP chips
نویسندگان
چکیده
منابع مشابه
Simultaneous QTL detection and genomic breeding value estimation using high density SNP chips
BACKGROUND The simulated dataset of the 13th QTL-MAS workshop was analysed to i) detect QTL and ii) predict breeding values for animals without phenotypic information. Several parameterisations considering all SNP simultaneously were applied using Gibbs sampling. RESULTS Fourteen QTL were detected at the different time points. Correlations between estimated breeding values were high between m...
متن کاملGenomic breeding value prediction and QTL mapping of QTLMAS2011 data using Bayesian and GBLUP methods
BACKGROUND The goal of this study was to apply Bayesian and GBLUP methods to predict genomic breeding values (GEBV), map QTL positions and explore the genetic architecture of the trait simulated for the 15th QTL-MAS workshop. METHODS Three methods with models considering dominance and epistasis inheritances were used to fit the data: (i) BayesB with a proportion π = 0.995 of SNPs assumed to h...
متن کاملGenomic breeding value prediction and QTL mapping of QTLMAS2010 data using Bayesian Methods
BACKGROUND Bayesian methods allow prediction of genomic breeding values (GEBVs) using high-density single nucleotide polymorphisms (SNPs) covering the whole genome with effective shrinkage of SNP effects using appropriate priors. In this study we applied a modification of the well-known BayesA and BayesB methods to estimate the proportion of SNPs with zero effects (π) and a common variance for ...
متن کاملEstimating genomic breeding values from the QTL-MAS Workshop Data using a single SNP and haplotype/IBD approach
Genomic breeding values were estimated using a Gibbs sampler that avoided the use of the Metropolis-Hastings step as implemented in the BayesB model of Meuwissen et al., Genetics 2001, 157:1819-1829.Two models that estimated genomic estimated breeding values (EBVs) were applied: one used constructed haplotypes (based on alleles of 20 markers) and IBD matrices, another used single SNP regression...
متن کاملComparison of five methods for genomic breeding value estimation for the common dataset of the 15th QTL-MAS Workshop
BACKGROUND Genomic breeding value estimation is the key step in genomic selection. Among many approaches, BLUP methods and Bayesian methods are most commonly used for estimating genomic breeding values. Here, we applied two BLUP methods, TABLUP and GBLUP, and three Bayesian methods, BayesA, BayesB and BayesCπ, to the common dataset provided by the 15th QTL-MAS Workshop to evaluate and compare t...
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ژورنال
عنوان ژورنال: BMC Proceedings
سال: 2010
ISSN: 1753-6561
DOI: 10.1186/1753-6561-4-s1-s9